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Musculoskeletal injuries may be painful or simply annoying, but they may also be responsible for the poor quality of life of a patient. We are talking about a global health problem, so, over the last two decades the studies have turned to the benefits that can arise from treatments originating from the field of regenerative medicine. Thus, stem cells - the base which the cells are formed for each organ of the body from – have been dynamically introduced to orthopaedic surgery, responding to a basic “problem”, namely the vulnerability of the muscles, ligaments, cartilage and tendons to regenerate.
Many famous athletes - among them, Tiger Woods and Rafael Nadal - have openly confessed that they prefer treatment with gRfor various problems, from sprains to chronic tendon injuries. In recent years, the research community has also shown interest in this promising treatment method, as several studies have been conducted on its effectiveness, regarding rapidly healing traumatic or degenerative lesions in muscles, tendons and ligaments.
The first applications of GF in patients started in the mid-1990s, and, according to the international literature, the factors influencing the success of the injectable treatment are dealing with the application area, the general state of the patient’s health, the extent of the damage and whether it is acute or degenerative.
In general, it is now considered to be a very effective treatment for chronic tendon lesions (such as the partial rotator cuff tear in the shoulder, lateral epicondylitis (tennis elbow), biceps, patellar or Achilles tendinities, and is recommended for sports injuries (strains, sprains) as the recovery time can be even halved.
In recent years, injectable autologous activated platelets and growth factors are also used during certain operations. They are further thought to help in the treatment of the arthritis of the knee.


Embryonic stem cells which are obtained from the umbilical cord at birth, are the most widely known ones. In adults, mesenchymal stem cells are obtained from the adipose tissue, usually from the patient’s abdomen, or when combined with surgery (e.g., an arthroscopy) from the area near the affected tissue. Laboratory isolation and stem cell culture are performed next - their placement will be effected either in the primitive form, or after they are transformed into chondrocytes and become connected to specific racks, which enter the affected part.
The “material” for growth factor therapies originates from the patient themselves: A small amount of peripheral blood is obtained in the orthopaedic clinic, the same way a standard blood test (blood sampling) is performed. Through a special treatment, the platelets are isolated and are then activated with calcium chloride or other means, so they can secrete their stored growth factors.


The injection is directly and accurately administered to the damaged area, through an ultrasound or x-ray (c-arm) guidance. The procedure lasts less than 20 minutes, it is painless, without any allergic reactions or complications.

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